We are a globally active clinical research institute and academic study group specializing in investigator-initiated and industry–academia collaborative trials in medical oncology and hematology. Our mission is to advance science-driven cancer research, accelerate the development of innovative therapies, and address key clinical questions that matter to patients and physicians alike.
Our research activities have a clear objective: to conduct and facilitate excellent clinical cancer research at the international level in order to improve the treatment and quality of life of cancer patients.
Our collaborative models offer academic and biotech partners clear advantages
Our team of physicians, who have years of expertise and current knowledge in medical care, are specialized in the fields of hematology, oncology, surgical oncology, palliative medicine, supportive therapy, and human genetics. Our founders are oncologists, and this expertise is a hallmark of IKF.
With well-established networks of almost hundreds of medical institutions, the best experts in their respective fields for every disease type, and the largest academic study groups in Germany and Europe, IKF has a powerful network that sets us apart.
IKF provides well-established access to routine clinical oncology environments through long-term collaborations with university hospitals, other large hospitals, and private oncology practitioners.
Institute of Clinical Cancer Research IKF at Northwest Hospital
We are a globally acting clinical research institution specializing in investigator-initiated and industry-academia collaborative clinical cancer research.
Founded by oncologists driven by a shared vision to make a global impact, our mission is to advance science-driven cancer research through collaboration between industry and academia.
By leveraging the strengths and expertise of both sectors we strive to conduct transformative research and provide answers to crucial clinical questions.
Excellence in Research
Our research activities have a clear objective: to conduct and facilitate excellent clinical cancer research at the international level in order to improve the treatment and quality of life of cancer patients. As we are not a pharmaceutical company, our real “product” is the gain of scientific knowledge, which we achieve through clinical trials with our partners that focus on patient-relevant endpoints such as survival and quality of life.”
Sponsored by our institution and conducted on an international scale, our investigator-initiated trials result from collaborative efforts between our internal experts and external partners, including esteemed physicians and oncologists from various university hospitals.
Our trials tackle crucial clinical questions and focus on optimizing therapies involving already approved compounds. We evaluate different drug combinations, modify doses or schedules, and test newly approved compounds in specific patient populations or therapy settings. Through these initiatives, we strive to uncover innovative approaches that improve treatment outcomes and enhance the quality of life for cancer patients. These trials have gained worldwide recognition for their significant impact on the field of cancer care.
Translational Research and IKF BioDataBank
We recognize the vital role of translational research in our study designs. We are dedicated to advancing our understanding of cancer pathogenesis and development, and to achieve this, we integrate translational elements into our research.
To facilitate researchers in gaining valuable insights, we collect various specimens such as tissue, blood, and stool samples whenever possible. These specimens, along with their associated clinical trial data, are curated in the IKF BioDataBank. This comprehensive resource houses thousands of tissue samples, providing an invaluable asset for studying cancer at the molecular level. To ensure the ethical use and access to these samples, the BioDataBank operates under a stringent governance framework.
In addition, IKF places special emphasis on clinical translation and re-translation within early clinical trials. Recognizing the urgent need for fast-tracked translation of promising compounds into the clinical setting, we have established the Platform Phase IIa Trials Initiative. This platform enables us to swiftly assess the clinical impact of early compounds and expedite their development process. By harnessing this platform, we aim to accelerate the translation of research findings into tangible benefits for patients.
We aim at improving personalized cancer therapy with our academic partners by establishing large networks and registries for molecular profiling. Our interactive PLATON Network (Platform for Analyzing Targetable Mutations) brings together comprehensive molecular profiling, extensive clinical data of cancer patients, QoL, education, and clinical trial information to advance cancer research and treatment.
The highly modular PLATON network also serves as a versatile structure for conducting substudies and translational subprojects. This network not only facilitates in-depth investigations but also functions as a platform for identifying patients with specific mutations for enrollment in clinical trials tailored to distinct molecular aberrations.
To learn more about the PLATON network visit the PLATON website. https://platon-network.de/
In addition to clinical trials, we conduct real-world studies in diverse healthcare settings. These studies provide valuable insights into the practical application of treatments, their effectiveness in routine care, and patient outcomes in real-world scenarios. By conducting research in real-life settings, we aim to bridge the gap between controlled clinical environments and the complexities of everyday clinical practice.
For that, IKF is the anchoring point for several registries on quality of life, patient-reported outcomes, and molecular research, such as PARAGON (Platform for Outcome, Quality of Life and Translational Research on Pancreatic Cancer), GISAR (German Sarcoma Registry), CONGENIAL (Comprehensive Genomic Profiling Project of The German-Registry of Incidental Gallbladder Carcinoma), and PERSUASION (New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma), which is a permanent platform that includes all types of biliary tract cancers (BTC).
Excellence in Research
Our research activities have a clear objective: to conduct and facilitate excellent clinical cancer research at the international level in order to improve the treatment and quality of life of cancer patients. As we are not a pharmaceutical company, our real “product” is the gain of scientific knowledge, which we achieve through clinical trials with our partners that focus on patient-relevant endpoints such as survival and quality of life.”
Sponsored by our institution and conducted on an international scale, our investigator-initiated trials result from collaborative efforts between our internal experts and external partners, including esteemed physicians and oncologists from various university hospitals.
Our trials tackle crucial clinical questions and focus on optimizing therapies involving already approved compounds. We evaluate different drug combinations, modify doses or schedules, and test newly approved compounds in specific patient populations or therapy settings. Through these initiatives, we strive to uncover innovative approaches that improve treatment outcomes and enhance the quality of life for cancer patients. These trials have gained worldwide recognition for their significant impact on the field of cancer care.
Translational Research and IKF BioDataBank
We recognize the vital role of translational research in our study designs. We are dedicated to advancing our understanding of cancer pathogenesis and development, and to achieve this, we integrate translational elements into our research.
To facilitate researchers in gaining valuable insights, we collect various specimens such as tissue, blood, and stool samples whenever possible. These specimens, along with their associated clinical trial data, are curated in the IKF BioDataBank. This comprehensive resource houses thousands of tissue samples, providing an invaluable asset for studying cancer at the molecular level. To ensure the ethical use and access to these samples, the BioDataBank operates under a stringent governance framework.
In addition, IKF places special emphasis on clinical translation and re-translation within early clinical trials. Recognizing the urgent need for fast-tracked translation of promising compounds into the clinical setting, we have established the Platform Phase IIa Trials Initiative. This platform enables us to swiftly assess the clinical impact of early compounds and expedite their development process. By harnessing this platform, we aim to accelerate the translation of research findings into tangible benefits for patients.
We aim at improving personalized cancer therapy with our academic partners by establishing large networks and registries for molecular profiling. Our interactive PLATON Network (Platform for Analyzing Targetable Mutations) brings together comprehensive molecular profiling, extensive clinical data of cancer patients, QoL, education, and clinical trial information to advance cancer research and treatment.
The highly modular PLATON network also serves as a versatile structure for conducting substudies and translational subprojects. This network not only facilitates in-depth investigations but also functions as a platform for identifying patients with specific mutations for enrollment in clinical trials tailored to distinct molecular aberrations.
To learn more about the PLATON network visit the PLATON website. https://platon-network.de/
In addition to clinical trials, we conduct real-world studies in diverse healthcare settings. These studies provide valuable insights into the practical application of treatments, their effectiveness in routine care, and patient outcomes in real-world scenarios. By conducting research in real-life settings, we aim to bridge the gap between controlled clinical environments and the complexities of everyday clinical practice.
For that, IKF is the anchoring point for several registries on quality of life, patient-reported outcomes, and molecular research, such as PARAGON (Platform for Outcome, Quality of Life and Translational Research on Pancreatic Cancer), GISAR (German Sarcoma Registry), CONGENIAL (Comprehensive Genomic Profiling Project of The German-Registry of Incidental Gallbladder Carcinoma), and PERSUASION (New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma), which is a permanent platform that includes all types of biliary tract cancers (BTC).
Excellence in Research
Our research activities have a clear objective: to conduct and facilitate excellent clinical cancer research at the international level in order to improve the treatment and quality of life of cancer patients. As we are not a pharmaceutical company, our real “product” is the gain of scientific knowledge, which we achieve through clinical trials with our partners that focus on patient-relevant endpoints such as survival and quality of life.”
Sponsored by our institution and conducted on an international scale, our investigator-initiated trials result from collaborative efforts between our internal experts and external partners, including esteemed physicians and oncologists from various university hospitals.
Our trials tackle crucial clinical questions and focus on optimizing therapies involving already approved compounds. We evaluate different drug combinations, modify doses or schedules, and test newly approved compounds in specific patient populations or therapy settings. Through these initiatives, we strive to uncover innovative approaches that improve treatment outcomes and enhance the quality of life for cancer patients. These trials have gained worldwide recognition for their significant impact on the field of cancer care.
Translational Research and IKF BioDataBank
We recognize the vital role of translational research in our study designs. We are dedicated to advancing our understanding of cancer pathogenesis and development, and to achieve this, we integrate translational elements into our research.
To facilitate researchers in gaining valuable insights, we collect various specimens such as tissue, blood, and stool samples whenever possible. These specimens, along with their associated clinical trial data, are curated in the IKF BioDataBank. This comprehensive resource houses thousands of tissue samples, providing an invaluable asset for studying cancer at the molecular level. To ensure the ethical use and access to these samples, the BioDataBank operates under a stringent governance framework.
In addition, IKF places special emphasis on clinical translation and re-translation within early clinical trials. Recognizing the urgent need for fast-tracked translation of promising compounds into the clinical setting, we have established the Platform Phase IIa Trials Initiative. This platform enables us to swiftly assess the clinical impact of early compounds and expedite their development process. By harnessing this platform, we aim to accelerate the translation of research findings into tangible benefits for patients.
We aim at improving personalized cancer therapy with our academic partners by establishing large networks and registries for molecular profiling. Our interactive PLATON Network (Platform for Analyzing Targetable Mutations) brings together comprehensive molecular profiling, extensive clinical data of cancer patients, QoL, education, and clinical trial information to advance cancer research and treatment.
The highly modular PLATON network also serves as a versatile structure for conducting substudies and translational subprojects. This network not only facilitates in-depth investigations but also functions as a platform for identifying patients with specific mutations for enrollment in clinical trials tailored to distinct molecular aberrations.
To learn more about the PLATON network visit the PLATON website. https://platon-network.de/
In addition to clinical trials, we conduct real-world studies in diverse healthcare settings. These studies provide valuable insights into the practical application of treatments, their effectiveness in routine care, and patient outcomes in real-world scenarios. By conducting research in real-life settings, we aim to bridge the gap between controlled clinical environments and the complexities of everyday clinical practice.
For that, IKF is the anchoring point for several registries on quality of life, patient-reported outcomes, and molecular research, such as PARAGON (Platform for Outcome, Quality of Life and Translational Research on Pancreatic Cancer), GISAR (German Sarcoma Registry), CONGENIAL (Comprehensive Genomic Profiling Project of The German-Registry of Incidental Gallbladder Carcinoma), and PERSUASION (New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma), which is a permanent platform that includes all types of biliary tract cancers (BTC).